Abstract: OBJECTIVE To study the effect of complex corydalis decumbens pers on therapeutic effect and hemorheology and cerebral blood flow and brain function in patients with cerebral infarction. METHODS One hundred and twenty cases were randomly divided into complex corydalis decumbens pers groups and control groups. Three-dimensional Doppler (TCD) and electroencephalogram (EEG) and hemorheology were examined before and after therapy in all cases. RESULTS After one month therapy the effective rate was 68.3% in complex corydalis decumbens pers groups and 56.7% in control groups，by Ridit analysis there was not significance difference in two groups，P>0.05. But a series of clinical symptom such as headache and dizziness and limbs aching pain were obviously improved. Cerebral blood flow and EEG and hemorheology were ameliorated in two groups，especially in complex corydalis decumbens pers groups. CONCLUSION complex corydalis decumbens pers may obviously improve clinical symptoms and promote cerebral blood flow and brain function in patients with cerebral infarction.