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    朱狄峰, 吴洪海, 吴国兰, 楼剑书, 何俏军, 杨波. LC-MS/MS法测定浸润麻醉豚鼠血浆中罗哌卡因浓度[J]. 中国现代应用药学, 2008, (3): 183-186.
    引用本文: 朱狄峰, 吴洪海, 吴国兰, 楼剑书, 何俏军, 杨波. LC-MS/MS法测定浸润麻醉豚鼠血浆中罗哌卡因浓度[J]. 中国现代应用药学, 2008, (3): 183-186.
    shu
    ZHU Di-feng, WU Hong-hai, WU Guo-lan, LOU Jian-shu, HE Qiao-jun, YANG Bo. Determination of Ropivacaine in Guinea Pig Plasma after Infiltration Anaesthesia by Liquid Chromatography-tandem Mass Spectrometry[J]. The Chinese Journal of Modern Applied Pharmacy, 2008, (3): 183-186.
    Citation: ZHU Di-feng, WU Hong-hai, WU Guo-lan, LOU Jian-shu, HE Qiao-jun, YANG Bo. Determination of Ropivacaine in Guinea Pig Plasma after Infiltration Anaesthesia by Liquid Chromatography-tandem Mass Spectrometry[J]. The Chinese Journal of Modern Applied Pharmacy, 2008, (3): 183-186.
    shu

    LC-MS/MS法测定浸润麻醉豚鼠血浆中罗哌卡因浓度

    Determination of Ropivacaine in Guinea Pig Plasma after Infiltration Anaesthesia by Liquid Chromatography-tandem Mass Spectrometry

      摘要
    • Abstract: OBJECTIVE To develop a sensitive and selective LC-MS/MS method for the determination of ropivacaine and pharmacokinetics in guinea pig plasma.METHODS After a simple sample preparation procedure by one-step protein precipitation with acetonitrile,the HPLC

       

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