枇芩颗粒剂体外抑制金黄色葡萄球菌和痤疮丙酸杆菌的作用

Bacteriostatic Action of Piqin Granules Against Staphylococcus Aureus and Propionibacterium Acnes in Vitro

摘要: 目的研究枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌的体外抑制作用。方法采用滤纸片或牛津杯的琼脂扩散法观察枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌的体外抑菌作用，同时定量测定枇芩颗粒剂对这2种菌的最低抑菌浓度。结果枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌均有明显抑菌作用，对金黄色葡萄球菌最低抑菌浓度为0.05 g·mL^-1，对痤疮丙酸杆菌最低抑菌浓度为0.10 g·mL^-1。结论枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌均具有明显的抑制作用。

Abstract: OBJECTIVE To study effect of Piqin granules on bacteriostatic action against Staphylococcus aureus and Propionibacterium acnes in vitro. METHODS The effect on bacteriostatic action against Staphylococcus aureus and Propionibacterium acnes were cultured by plating method and oxfordcup, and then by test tube continuously dilution in order to observe their minimal inhibitory concentration(MIC). RESULTS Piqin granules were highly sensitive to Staphylococcus aureus and Propionibacterium acnes in vitro. The MIC was 0.05 g·mL^-1 against Staphylococcus aureus; and the MIC was 0.10 g·mL^-1 against Propionibacterium acnes. CONCLUSION Piqin granules show satisfactory bacteriostatic action against the Staphylococcus aureus and Propionibacterium acnes.