Abstract: OBJECTIVE To research on the formulations of lappaconitine cataplasm by means of rheology METHODS The gel strength was measured by SMS Texture Analyser and the fillers of lappaconitine cataplasm were preliminary screen out. The rheology was measured by Malvern Rotational Rheometer and then the dosage of fillers and tackifiers were investigated and determined. RESULTS Aerosol could increase gel strength most remarkably and was designated as filler. Rheological measurement showed the aerosol could increase elastic modulus(G′) and viscous modulus(G″) simultaneously, but the former was more remarkable and the optimal content was 2.5%; All kinds of tackifiers could increase G″ remarkably. PVA have the least influence on G′ and was screened out as tackifier. The adhesiveness examination according to the 2015 edition of Chinese Pharmacopoeia (Part Ⅳ) verified the optimized lappaconitine cataplasm has good adhesive property. CONCLUSION Rheological parameters are useful tools for screening out the formulations of cataplasm.