Abstract: OBJECTIVE To develop a method for simultaneous determination of 6 kinds of phthalate esters in injections passed through infustion set by dispersive liquid-liquid microextraction-GC-MS. METHODS A mixture of extraction solvent (toluene containing benzyl benzoate as internal standard) and surfactant (hexadecylytrimethylamminium bromide) solution was injected into 5.0 mL of sample solution to form an emulsion by the assistance of 1 min vortex agitation. After extraction and phase separation by centrifugation under 4 000 r·min^-1 for 5 min, the toluene extract were collected and analyzed by GC-MS. RESULTS The method exhibited enrichment factor values of 6 kinds of phthalate esters ranging from 174 to 280, the 1imits of detection(LOD) ranged from 0.007 to 0.04 ng·mL^-1 (S/N=3). The recoveries were from 97.8% to 101.2% with relative standard deviations (RSD) of 0.44%-0.93%. DBP and DEHP were detected in some injections passed through infustion set. CONCLUSION The method is sensitive, simple and can be applied for simultaneous determination of 6 phthalate esters in injections.