Abstract: OBJECTIVE To explore the effects of processed products of Aconiti Lateralis Radix Praeparata on auricular microcirculation in mice with Yang deficiency. METHODS The mice were randomly divided into 14 groups: the control group, the model group, experimental groups (Heishunpian groups, high temperature groups, high pressure groups, microwave treatment group), each set were divided into high, medium and low drug dosage(0.75, 3.00, 5.63 g·kg^-1), all the mice were given intragastric administration for 9 d. Twenty-four hours after the last administration, with the vascular diameter of vein and artery and capillary network cross points were measured by microscopic micrometer. The dose-effect relationship was analyzed according to the content of alkaloids of processed products. RESULTS Compared with the model group, the vascular diameter of vein and artery were increased of the processed products groups except 0.75 g·kg^-1 microwave treatment group, and the capillary network crossover points of the processed products groups were also increased(P<0.05). The effect was positively correlated with the dose. Compared with Heishunpian group, the vascular diameter of artery was significantly increased of high-pressure processed products with the dose of 5.63 g·kg^-1(P<0.05). Comparing 4 processed products administered group with the same dose, the vascular diameter of vein, artery and capillary network cross points of high pressure processed products were the highest. CONCLUSION The high pressure processed products could significantly enhance the microcirculation of mice with Yang deficiency, its effect is better than Heishunpian, high temperature processed products, or microwave processed products.