黄三七化学成分的研究

Study on the Chemical Constituents from Souliea Vaginata (Maxim.) Franch

摘要: 目的研究黄三七的化学成分。方法采用多种色谱方法对黄三七全草的乙醇提取物进行分离纯化，并应用现代波谱技术对得到的化合物进行结构鉴定。结果共分离得到6个环菠萝蜜烷型三萜类化合物，分别鉴定为cimilactoneA( 1 )、23-Epi-26-deoxyactein( 2 )、soulieosides I( 3 )、neocimicigenoside B( 4 )、asiaticoside A( 5 )、25-O-acetylcimigenol-3-O-β-D- xylopyranoside( 6 )。结论环菠萝蜜烷型三萜类化合物是黄三七的特征性成分，化合物 1 、 4 和 5 为首次从该属植物中分离得到。

Abstract: OBJECTIVE To study the chemical constituents of the ethanol extract from the plant Souliea vaginata (Maxim.) Franch. METHODS The chemical constituents were isolated by multi-chromatographic methods as silica gel, macroporous resin, MCI, Sephadex LH-20, C₁₈-reversed-phase chromatography. The structures were identified on the basis of chemical methods and spectroscopic evidence. RESULTS Six cycloartane triterpenoid compounds were isolated and identified as cimilactone A ( 1 ), 23-Epi-26-deoxyactein ( 2 ), soulieosides I ( 3 ), neocimicigenoside B ( 4 ), asiaticoside A ( 5 ), 25-O- acetylcimigenol-3-O-β-D-xylopyranoside ( 6 ). CONCLUSION Cycloartane triterpenoids existed as characteristic constituents in Souliea vaginata (Maxim.) Franch. Compound 1 , 4 and 5 were separated from this species for the first time.