Abstract:
OBJECTIVE Pharmaceutical investigate for the scoring study based on valsartan tablets which were scored on one side. METHODS Tablets splitting method of inspecting and loss of mass test, dissolution curve and friability test for segmentation were researched. RESULTS Valsartan tablets scored on one side could be splitted easily, the loss of mass was less than 0.16%. Dissolution curve of segmentation was smilar with the whole tablet. Result of friability could be met the criterion of Ch.P. CONCLUSION Tablet segments of valsartan tablets which scored on one side can be spiltted uniformly and released normally. The score benefits the clinical dose adjustments.