Abstract: OBJECTIVE To determine the insoluble particles in salvianolate injection in Pharmacy Intravenous Admixture Service(PIVAS) at different drug concentrations, different solvents and different time. METHODS According to the statistics of the prescription, admixed in the PIVAS and measured the quantity of insoluble particles in salvianolate solution by light blockage method specified in ch.P 2010. RESULTS While 5% glucose or 0.9% sodium chloride injection was used as solvent, the number of insoluble particles conformed to the ch.P 2010 in 8 h. The number of small particles (size≥2 μｍ) significantly bigger than the large particles(size≥10 μｍ)(P<0.05). In the high concentration(0.8 g·L^-1) solution, the number of insoluble particles was bigger than the lower concentrations(0.4 g·L^-1). CONCLUSION The 5% glucose or 0.9% sodium chloride injection can be used as the solvent, in according to the drug specification low concentration(0.4 g·L^-1) should be choosed and the solution should be used for patients as soon as possible.