Abstract:
OBJECTIVE to observe the clinical efficacy of Yiqi Wenjing recipe in treating postmenopausal osteoporotic hip fractures by changing bone mineral density (BMD), SF-36 quality of life score. METHODS The postmenopausal osteoporotic hip fracture patients were objected for study, who visited the Second Affiliated Hospital of Zhejiang Chinese Medical University from June 2013 to August 2014. the 120 patients met the inclusion criteria were randomly divided into three groups, the Yiqi Wenjing recipe group, basic medication group and Xianlinggubao group, 40 cases in each group. Basic medication group given Calcium Carbonate Chewable D3 1.0 g and alfacalcidol capsules everyday; Xianlinggubao group was based on basic medication group to plus Xianlinggubao capsule; Yiqi Wenjing recipe group was based on basic medication group to plus Yiqi Wenjing recipe. All of the groups gave 6 months treatment. measured bone mineral density (BMD), SF-36 quality of life score. RESULTS After 6 months of treatment, the BMD of Yiqi Wenjing recipe group and Xianlinggubao group were both increased slightly(P<0.05), which were both had advantage over basic medication group(P<0.05). However, there were significant differences in the two groups compared the average rate of change(P<0.05); the average increase in BMD with Yiqi Wenjing recipe group (2.21%) were higher than the Xianlinggubao group (1.95%). In all groups after treatment, all dimensions of quality of life score increased significantly(P<0.05). Four dimensions including the physiological function, vitality, physiological function, social function in Yiqi Wenjing recipe group were improved obviously than basic medication group(P<0.05). while four dimensions including somatic pain, mental health, emotional functioning, general health had no significant difference compared with other groups. CONCLUSION Yiqi Wenjing recipe in preventing and treating of postmenopausal osteoporotic hip fractures can effectively improve the quality of life, promote the BMD.