Abstract: OBJECTIVE To establish a sensitive and specific HPLC method and a standard fingerprint for quality control of Corydalis Rhizoma dry goods. METHODS Diamonsil C₁₈ column(4.6 mm×300 mm, 5μm) was adopted, gradient elution was applied with mobile phase A(acetonitrile) and mobile phase B(triethylamine adjusted to pH 6.0). The flow rate was 1.0 mL?min^-1, the detective wavelength was 230 nm, the column temperature was 25 ℃ injection volume was 10 μL. RESULTS HPLC fingerprints of different source of the Corydalis Rhizoma were established. The semblance was calculated. The results of methodological study met the technical requirements for fingerprint. CONCLUSION This method is accurate, reproducible and provides a scientific basis for quality evaluation of the Corydalis Rhizoma.