临床药师干预门诊超说明书用药现象效果分析

Analysis of the Effect of Clinical Pharmacists Intervening in Outpatient Off-label Uses

摘要: 目的评价笔者所在医院临床药师干预门诊超说明书用药的效果。方法回顾性统计2011年2月门诊处方超说明书用药情况，根据超说明书用药频次最高的10种药品的使用情况，进行系统评价，根据实际进行合理用药软件的设置，从而在医师开具处方时会有软件弹出警示窗口进行提醒。统计2014年2月该10种药品相同超说明书用药情况，与干预前比较。结果除1种药品因品种调整未再使用，无法比较外，其他9种药品超说明书用药情况均有不同程度的下降。结论经过临床药师专业的系统评价，使用合理用药软件提醒对控制医师超说明书用药的情况是有利的。

Abstract: OBJECTIVE To evaluate the effect of clinical pharmacists intervening in outpatient off-label uses. METHODS To retrospective analyze the outpatient off-label uses in Feb. 2011, choose the top 10 medicines that off-label use to system review and install rational drug use software. The software can give a warning window to remind the doctors when they prescribe off-label use. Analyze the outpatient off-label uses in Feb. 2014 and compare to the off-label uses before the intervention. RESULTS All of the off-label uses decrease compared to the off-label use before the intervening besides one medicine was not use any more. CONCLUSION It react to the phenomenon of off-label uses with system assessing and soft reminding by clinical pharmacists.