Abstract: OBJECTIVE To find the problems and insufficiencies in Adverse Drug Reaction(ADR) monitoring work by analysis of the current situation of ADR monitoring in our hospital and to explore the effective training mode of ADR monitoring in medical institutions. METHODS ADR reports from 2009 to 2013 of our hospital were analyzed retrospectively and the investigation of ADR cognition for the medical staffs was carried out in order to learn about ways to obtain ADR information by the medical staffs and their training status. Moreover, the subjective and objective factors about spontaneously ADR reporting were found out. RESULTS The number of average annual ADR reports increased significantly in our hospital from 472 cases of 2009-2012 to 644 cases of 2013 after a series of targeted measures had been taken , the increase rate was 36.4%.Quality of the reports had also been greatly improved. New and serious ADR reports of 2013 increased by 681.8%. Meanwhile, the proportion of ADR reporting subject changed from pharmacists to doctors or nurses in order to enhance the ADR reports timeliness. As a key monitoring drug , the serious ADR caused by Allopurinol had also been greatly improved with average annual ADR reports increasing from 1.5 cases to 7 cases. CONCLUSION In our hospital the new mode of training on ADR monitoring established at present stage in our hospital is feasible and worth being adopted by other hospitals. But we must realize that ADR monitoring is a systematic project which needs long-term perseverance and intensive training.