Abstract: OBJECTIVE To investigate the stability of glycyrrhizic acid phospholipid complex self-emulsifying concentrated solution. METHODS Low temperature test(4 ℃), temperature cycling test(4 ℃, 37 ℃) and long-time test were used to study the emulsification time and emulsifying effect. The content of the samples were evaluated by HPLC. RESLUTS Items of the samples were according with the quality standard by cold testing of 7 d, temperature cycling testing of 7 d, long-time testing for 6 months. CONCLUSION Glycyrrhizia acid phospholipid complex self-emulsifying concentrated solution is clear and transparent with stable quality.