Abstract: OBJECTIVE To illustrate the importance and necessity of clinical pharmacists in making clinical drug treatment decisions by the pharmaceutical care practice for one child with staphylococcal scalded skin syndrome. METHODS Clinical pharmacists participated therapy scheme to give reasonable advise in the light of pathogenetic condition change, and instructed parents about medicine education simultaneously. RESULTS With the participation of clinical pharmacists, clinical doctor could adjust the therapy scheme to make effective and rational treatment. CONCLUSION The work pattern is scientific and rational that clinical pharmacists cooperate closely with clinicians and instructe patients in medicine education, it can optimize drug treatment and ensure reasonable, safe and effectie of clinical application.