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    住院患者中药注射剂临床应用的药物相关性问题调查和干预研究

    Investigation and Intervention Study for Drug Related Problems of Traditional Chinese Medicine Injections in Clinical Application of Inpatients in the Hospital

      摘要
    • 摘要: 目的 建立中药注射剂临床应用合理性评价方法，研究中药注射剂临床使用中的药物相关性问题(drug-related problems，DRPs)。方法 采用国际通用的西班牙药物相关性问题研究方法(Granada-Ⅱ分类法)对住院患者中药注射液相关性问题进行临床使用必要性、安全性、有效性的研究。结果 中药注射剂各类DRPs总数为401个，共涉及到28种中药注射剂，累计产生472 DRPs药次，在临床药师的干预下，DRPs的发生率随着时间的发展呈下降趋势。结论 西班牙的药物相关性问题研究方法(Granada-Ⅱ分类法)适用于中药注射剂合理使用的研究，不同类别的中药注射剂DRPs发生率并不相同，并且可通过临床药师的干预来减少其发生率。

       

      Abstract: OBJECTIVE To establish reasonable evaluation method for clinical application of traditional Chinese medicine injections. To study the drug related problems of traditional Chinese medicine injection in the clinical use. METHODS With the investigation methods of drug related problems of the Spanish Granada-Ⅱ Classification, we studied the clinical effectiveness, necessity, safety of traditional Chinese medicine injections in the hospital. RESULTS The total number of DRPs was 401, 28 kinds of traditional Chinese medicine injections were involved. The drugs accumulated generating 472 DRPs, with the intervention of the clinical pharmacist, the incidence rate of DRPs decreased. CONCLUSION The methods of drug related problems in Spain Granada-Ⅱ Classification can be used in research on the rational use of traditional Chinese medicine injections in the hospital. The DRPs rate of different kinds of traditional Chinese medicine injection is not the same, and the clinical pharmacist interventions can reduce the rate of incidence of DRPs.

       

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