了哥王的化学成分研究

Chemical Constituents of Wikstroemia Indica

摘要: 目的研究了哥王Wikstroemia indica (L.) C. A. Mey.化学成分。方法运用硅胶、凝胶等多种色谱技术对了哥王的化学成分进行研究，并根据理化性质和波谱数据鉴定化合物结构。结果从了哥王85%乙醇提取物的醋酸乙酯和正丁醇萃取部位分离并鉴定了9个化合物，分别为西瑞香素(daphnoretin)、柚皮素(naringin)、3,5,7-二羟基-4'-甲氧基二氢黄酮醇(3,5,7-trihydroxy-4′-methoxy-dihydroflavonol)、对羟基苯甲酸(4-hydroxybenzoic acid)、苯甲酸(benzoic-acid)、伞形花内酯(umbdheforne)、daphnogitin、sikokianin B、芫花素(genkwanin)。结论化合物2~5为首次从该植物中分离得到。

Abstract: OBJECTIVE To study the chemical constitutents from Wikstroemia indica (L.) C. A. Mey. METHODS Silica gel column, Sephadex LH-20 column chromatography were used for separation and purification of the compounds and extensive spectral analysis spectrum were employed for structural elucidation. RESULTS Nine compounds were isolated from EtOAc and n-butanol fraction of the 85% ethanol extract of the W. indica and identified as daphnoretin, naringin, 3,5,7-trihydroxy-4′-methoxy-dihydroflavonol, 4-hydroxybenzoic acid, benzoic-acid, umbdheforne, daphnogitin, sikokianin B, and genkwanin. CONCLUSION Compounds 2-5 are obtained from the plants of W. indica for the first time.