Abstract: OBJECTIVE To introduce the progress of the combined treatment of docetaxel and chemotherapy for non-small cell lung cancer. METHODS By investigating the national and international literatures, the clinical effects and adverse reactions of docetaxel combining with platinum agents and non-platinum drugs were discussed. RESULTS The efficacy was definite and adverse effects were light in treatment of non-small cell lung cancer by docetaxel combining with chemotherapy. CONCLUSION The combined therapy is expected to solve the single-agent problem of low effects and provide the clinical guidance.