Abstract: OBJECTIVE To review the quality control of Notopterygii Rhizoma et Radix and to provide a reference and evidence for further research. METHODS Collecting and analyzing papers about morphological identification, chemical component analysis, fingerprint chromatography, the heavy metals and inorganic elements in Notopterygii Rhizoma et Radix for the past few years. RESULTS AND CONCLUSION The methods of determination of the major contents of Notopterygii Rhizoma et Radix include TLC scanning, HPLC, GC-MS, and LC-MS. The HPLC method was most commonly used. The content analysis results showed that chemical constituents of Notopterygii Rhizoma et Radix from different habitats varied significantly. Furthermore, there were few research on the determination of pesticide residues, heavy metals and the equivalence study between wild and cultivated Notopterygii Rhizoma et Radix, therefore this herb need further study.