Abstract: OBJECTIVE Analysis of irrational drug use and come up with strategies. METHODS Access to the Court from July 2007 to December 2008 the prescription of irrational drug use statistics classified and analyzed retrospectively. RESULTS Unreasonable prescription drugs accounted for 0.42% of the total number of available performance for the improper route of administration, dose unreasonable solvent improper delivery time interval, combined improperly, such as course of treatment is too long. CONCLUSION Unreasonable for the hospital drug use should be strengthened publicity on rational drug use training and institution building, doctors and pharmacists should cooperate closely to promote rational drug use.