Abstract: OBJECTIVE To probe into the situation of rational drug use in our hospital so as to provide reference for the intervention of irrational drug use. METHODS All the outpatient prescriptions in July in our hospital were subjected to statistical analysis using international investigation indicators for rational drug use. RESULTS The percentage of outpatients treated without drugs was 77.47%. The average number of drugs prescribed was 1.60. The percentage of outpatients that received antibacterial, injections, essential drugs and medical insurance drugs were 15.22 %, 65.47%, 75.61% and 97.65%, respectively. They accounted for 14.83%, 13.11%, 42.59% and 94.44% of total drug cost, respectively. The percentage of drugs prescribed by generic name was 99.95%. The average drug cost per prescription was 43.74 Yuan. CONCLUSION The use of drugs for outpatients in our hospital was basically rational. However, the use of essential drugs should be enhanced.