Abstract: OBJECTIVE To observe the effect of Schisandra Chinensis Baill distilled by ethanol on the ability of learning and memory in memory impairment mice model induced by repeated cerebral ischdmia-reperfusion. METHOD The mice were randomly divided into six groups,respectively irrigating the groups with Nimodipine suspension,ginkgo leaf tablet suspension, large and small doses of Schisandra Chinensis Baill distilled by ethanol, sham group (blank and the model group for the same volume of saline, Once a day,15days for delivery, Mice model of cerebral ischemia-reperfuqion injury was established by bilateral common carotid artery blocking.48 hours after operation, begin the experiment of behavior. Step down test: the mice were put into the apparatus of step down for discipline and the training, 24 hours later, retest the memory of the mice, register the delitescence of the set up and the times of the mistakes in 5 minutes. Evading dark test: the mice were put into the darkroom, turn on the electrical source for discipline and the training, 24hours later, retest the memory of the mice .Register the delitescence of enter into the darkroom and the tip-and-run times. RESULTS Step down test: the large doses of Schisandra Chinensis Baill distilled by ethanol could notably prolong the latent phase of getting an electric shock，and could obviously decrease the error times in Step down tests; Evading dark test: the large doses of Schisandra Chinensis Baill distilled by ethanol could markedly prolong the latent phase for model mice in learning tests, and could notably decrease the error times in learning tests. CONCLUSION Schisandra Chinensis Baill distilled by ethanol could significantly improve on the ability of learning and memory of memory impairment mice model induced by repeated cerebral ischdmia-reperfusion.