复方马来酸氯苯那敏酊的制备及疗效观察

Preparation and Clinical Observation of Compound Chlorphenamine Maleate Tincture

摘要: 目的研制复方马来酸氯苯那敏酊的制备方法，观察其临床疗效。方法以马来酸氯苯那敏、氢化可的松为主药，以75%乙醇为溶媒，用常规方法制备。对瘙痒症、神经性皮炎各80例病人进行疗效观察。结果制剂稳定性好，治疗有效率为91.25%、90%。结论复方马来酸氯苯那敏酊安全、有效。

Abstract: OBJECTIVE The preparation and clinical effects of compound chlorphenamine maleate tincture were designed and studied.METHODS Compound chlorphenamine maleate tincture was prepared by regular methods with chlorphenamine maleate and hydrocortisone as main drug,75% alcohol as sovent.Eighty patients with pruritus and neurodermitis respectively were treated by compound chlorphenamine maleate tincture .RESULTS The preparation was stable.The total effective ratio were 91.25% and 90% respectively. CONCLUSION Compound chlorphenamine maleate tincture was safe and effective.