大剂量甲氨蝶呤在急性淋巴细胞白血病患儿体内的药动学研究
Pharmacokinetics of High-Dose Methotrexate Infusion in Children with Acute Lymphoblastic Leukemia
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Abstract: OBJECTIVE To evaluate the pharmacokinetics of methotrexate(MTX)in children with acute lymphoblastic leukemia(ALL)treated with high-dosage infusion of MTX and combination with calcium folinate(CF)rescued.METHODS The serum samples were collected at differen
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