离子敏感型毛果芸香碱眼用原位凝胶的制备及其初步药效学考察
Study on the Preparation of Ion-sensitive in Situ Gel of Pilocarpine Nitrate and Its Preliminary Pharmacodynamics
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Abstract: OBJECTIVE To study the preparation of ion-sensitive in situ gel of pilocarpine nitrate(PN) using sodium alginate and HPMC as base to increase the effect and decrease the administration frequency.METHODS To prepare in situ gel of PN,the best composition of