环氧合酶-2和5-脂氧化酶双重抑制剂的研究进展
Advances in the Research on the Cyclooxygenase-2 and 5-Lipoxygenase Dual Inhibitors
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Abstract: Classical Non-Steroidal Anti-Inflammatory Drugs(NSAIDs)and selective Cyclooxygenase-2(COX-2)inhibitors present GI damage and diverse side effects for the treatment of inflammatory disease,which limited their clinical development.These compounds with equal