抗精神病药阿立哌唑的合成工艺改进
Improved Synthesis of Antipsychotic Drug Aripiprazole
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Abstract: OBJECTIVE To improve the synthetic procedure of antipsychotic drug aripip-razole.METHODS Aripiprazole was synthesized via four steps starting from m-Anisidine. RESULTS Aripiprazole was prepared in an overall yield of 40%.The structure of the target compou