双(S)-萘普生甲酯的合成
Synthesis of Bis (S)-Naproxen Methyl Ester
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Abstract: OBJECTIVE Bis(S)-Naproxen methyl ester was designed and synthesized.METHODS The target compound was synthesized by the reaction of(S)-naproxen with chloromethyl ester of naproxen in the presence of K2CO3.The chloromethyl ester of naproxen was synthesized