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    (S)-(+)-氟比洛芬的合成

    New preparation of(S)-(+)-flurbiprofen

      摘要
    • Abstract: OBJECTIVE To synthesize S-enantiomer of non-steroids anti-inflammation drug flurbiporfen.METHODS 2-Fluoroaniline was brominated with 1,3-dibromo-5,5-dimethylhydantoin,then condensed with benzene to give 2-fluoro-4-bromo-biphenyl,which reacted with sodium

       

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