用两种不对称催化反应合成紫杉醇C13侧链

    Synthesis of taxol C13 side chain using two catalyzed asymmetic reaction

    • Abstract: OBJECTIVE To develop a simple and economical method to achieve taxol side chain,(2R,3S)-isoproplyl-3-benzamido-2-hydroxy-3-phenylpropionate.METHODS The taxol C13 side chain with high ees could be prepared from asymmetric aminohydroxylation(AA) and dihydro

       

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