阿德福韦酯在大鼠体内的药代动力学和组织分布特性研究
adefovir dipivoxil in rats
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Abstract: OBJECTIVEThe pharmacokinetic properties of adefovir dipivoxil were studied in rats. METHODSUpon oral administration of adefovir dipivoxil at 0.3, 1.0, 3.0 mg Kg-1, plasma samples were obtained at intervals during the 24 h postdosing and were analyzed for