离子对液相色谱法测定人血浆中替米沙坦的浓度及药动学研究
Ion-pair HPLC determination and pharmacokinetic study of telmisartan in human plasma
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Abstract: OBJECTIVE To establish an HPLC method for the determination of telmisartan concentration in plasma,and to investigate the pharmacokinetics of telmisartan in Chinese healthy volunteers.METHODS The chromatographic separation was achieved on a Shim-pack VP-O