半乳糖化季铵壳聚糖衍生物的设计、合成和表征
Design,synthesis and characterization of N-trimethyl chitosan derivatives having pendant galactose residues
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Abstract: OBJECTIVE To synthesize and characterize N-trimethyl chitosan derivatives having pendant galactose residues for potential gene delivery carriers for hepatocyte-targeting.METHOD Firstly,a water-soluble N-trimethyl chitosan derivatives(TMCS) was prepared.To