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    大鼠肝微粒体中美西律对映体氧化代谢的立体选择性研究

    Study on the stereoselectivity of oxidation metabolism of mexiletine enantiomers in rat liver microsome

      摘要
    • Abstract: OBJECTIVE To Study the stereoselectivity of oxidation metabolism of mexiletine enantiomers in rat liver microsome.METHODS The time course and the parameters of enzymatic kinetics of mexiletine enantiomers,Vm and Km,were determined by a capillary gas chrom

       

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