液相色谱-串联质谱法测定人血浆中劳拉西泮的浓度及其在生物等效性研究中的应用
Determination of lorazepam in plasma by LC/MS/MS and its application in the bioequivalence study
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Abstract: OBJECTIVE To establish a LC/MS/MS method for determination of lorazepam in plasma and to study its bioequivalence. METHODS 0.3mL of the plasma sample was pipetted into a conical tube, 0.6mL internal standard solution containing diazepam in acetonitrile wa