特非那定片溶出度测定

    Determination Dissolution of six commercial terfenadine tablets

    • 摘要: 目的评价市场上6个批号的特非那定片的质量。方法采用桨法作为溶出度测定法,HPLC作为特非那定浓度测定方法,再通过weibull's方程获得溶出度参数。结果仅有2个批号的特非那定片达到卫生部部颁标准。结论我们应该关注市场上特非那定片的质量。

       

      Abstract: OBJECTIVETo evaluate the drug quality in vitro of six commercial terfenadine tablets. METHODThe initial dissolution rate were measured using rotating paddle method. HPLC-method was used to determine the concentration of terfenadine and the Weibull's equat

       

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