比色法测定缓释片中羟丙甲纤维素
Determination of HPMC in delayed-release tablets by colorimetry
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摘要: 目的 建立测定制剂中羟丙甲纤维素(HPMC)含量的方法。方法 采用二苯胺和HPMC在高温下显色反应,分光光度法测定。结果 具良好的线性范围和回收率,测定方法可靠。结论 能作为制剂中HPMC含量测定的方法。Abstract: OBJECTIVE To develop a method for determination of HPMC in delayed-release tablets.METHOD HPMC was reacted with diphenylamine at high temperature to produce the colur product and determined by colorimetry.RESULTS The method had a good linear range and rec