咪康唑中间体1-(2,4-二氯苯基)-2-(1-咪唑基)乙醇合成新工艺

    Synthesis of 1-(2,4-dichlorophenyl)-2-(1-imidazolyl)ethanol

    • Abstract: OBJECTIVE To synthesize 1-(2,4-dichloropheny1)-2-(1-imidazoly1)ethanol. METHOD 1-(2,4-dichloropheny1)-2-(1-imidazoly1)ethanol, the important intermediate of miconazole, was synthesized by epoxidation of 2,4-dichloropheny1aldehyde with sulphonium ylide a

       

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