高效液相色谱-质谱联用法测定人血浆中奥昔布宁的浓度
Determination of oxybutynin in human plasma by HPLC-MS
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Abstract: OBJECTIVE To develop a HPLC ESI MS method for determination of oxybutynin in human plasma. METHOD The mobile phase was composed of 0.01mol/L ammonium acetate/water: methanol(15:85),phenoprolamine hydrochloride was used as internal standard. Plasma sam