MDP-阿霉素脂质体交联物治疗大鼠成骨肉瘤的药效学研究
Study on the pharmacodynamics of the adriamycin liposome conjugated MDP on UMR 106 osteosarcoma tumor model
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Abstract: OBJECTIVE:To prepare adriamycin liposome conjugated with MDP (Methylenediphonate,MDP LADM) and observe its therapeutic effect on UMR106 osteosarcoma tumor model in rat, as well as comparing it with adriamycin liposome (LADM) and free adriamycin(ADM) . ME