交联聚维酮对维A酸片溶出度的影响

Crospovidone effects on the dissolution rate of tretinoin tablets

摘要: 目的:研究崩解剂交联聚维酮对维A酸片溶出度的影响。方法:采用交联聚维酮不同用量,不同加入方法,放置时间和再次加工。结果:交联聚维酮不同用量,不同加入方法对溶出度有显著影响,放置时间和再次加工对溶出度无影响。结论:应用交联聚维酮应考虑其用量和加入方法

Abstract: OBJECTIVE:To study crospovidone effect on the dissolution rate of tretinoin tabets. METHOD:It is tested with the different contents of crospovidone,the different manufactured ways, the stored times, and tablets re preparation. RESULTS:There were signific