应用不同催化剂合成邻氨基苯甲腈的研究

Study on the synthesis of o-amino benzonitrile using different catalysis

摘要: 目的:研究邻氨基苯甲腈的合成方法。方法:采用醇碱、路易斯酸及金属氧化物等为催化剂,以靛红3 肟为原料合成邻氨基苯甲腈。结果:合成的产率为71.2 % ,结构经熔点确证。结论:碱性催化剂优于路易斯酸性催化剂,金属氧化物催化适合于工业化生产。

Abstract: OBJECTIVE:To study the synthesis of o-amino benzonitrile.METHOD:Using basic, lewis acid and metal oxide as catalysis, o-amino benzonitrile was synthesized from Isatin.RESULTS:The total yield of o amino benzonitrile was 71.2%. The final product was identi