白三烯拮抗剂ONO-1078对小鼠持续性局灶性脑缺血的作用
Effect of ONO-1078, a leukotriene antagonist, on permanent focal cerebral ischemia in mice
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Abstract: OBJECTIVE:To determine whether ONO-1078 4-oxo-8-p-(4-phenylbntyloxy)benzoyl-amino-2-(tetrazd-5-yl)-4H-1-benzopyran hemihydrate,a potent leukotriene antagonist, has a protective effect on focal cerebral ischemia in a mouse model. METHOD:Focal cerebral