1-甲基-3-正丙基吡唑-5-甲酸乙酯的合成(英文)

Synthesis of 1-methyl-3-n-propylpyrazole 5-carboxylic acid ethyl ester

摘要: 目的:合成标题化合物,并进行工艺改进。方法:以2 -戊酮和草酸二乙酯为原料,经三步反应合成了产物。结果:反应的总收率为4 7.7%。合成的各步产品经元素分析、红外和核磁共振光谱确证。结论:改进的工艺具有反应温度低、时间短等优点,并提高了收率。

Abstract: OBJECTIVE:To synthesize the title compound and improve of the process. METHOD:The title compound was synthesized from methyl n propyl ketone and diethyloxalate via three steps. RESULTS:The total yield was 47.7% on the basis of methyl n-proplyl ketone. Th