依替菲宁的合成

Synthesis of Etifenin

摘要: 目的:改进肝胆显像剂配基依替菲宁的合成方法。方法:该化合物以2 ,6 -二乙基苯胺为原料,改进文献工艺制备而成。所得产物经红外光谱、核磁共振等分析确证结构。结果:工艺简单、产品易得、收率高于文献报道。结论:此合成路线完全可行。

Abstract: OBJECTIVE:To synthesize N-(2,6-Diethylphenylcarbamoylmethyl) iminodiacetic acid(Etifenin),a precursor of hepato-biliary imaging agent.METHOD:Target molecular was synthesized from 2,6-diethylaniline,with the improved processes.Chemical structures of produc