微球给药系统的工艺优化研究
Optimization of the preparation of microsphere drug delivery system
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摘要: 目的:阐述微球制备工艺中的优化技术。方法:检索近年来国内外文献并进行整理和归纳。结果:单因素设计、正交设计、均匀设计、因子设计是目前微球工艺中常用的优化方法。结论:通过上述方法优化微球的制备工艺,可在一定条件下达到经济、高效的目的,更理想的优化技术尚有待研究Abstract: OBJECTIVE:To illustrate the optimized technique applied to microspheres preparation.METHOD:Recent literature were looked up,collated and summarized.RESULTS:Single factor design,orthogonal design,uniform design and factorial design are widely used for the
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