帕米膦酸二钠的合成

Synthesis of disodium 3-amino-1-hydroxy-propilidene-1,1-diphosphonate

摘要: 目的:合成二钠3 -氨基-1 -羟基-亚丙基-二膦酸盐(帕米膦酸二钠)。方法:有、无溶剂的两种合成路线,并对工艺进行改进。所得产物经元素分析,红外光谱,质谱等分析确证结构。结果:两种路线均可合成目标化合物。路线A收率高于路线B。结论:溶剂的加入使本反应体系均一,有利于产物生成

Abstract: OBJECTIVE:To synthesize disodium 3-amino-1-hydroxy-propilidene-1,1-diphosphonate.METHOD:Two processes had been improved(with or within solvent).Chemical structures of products were confirmed by element analysis,IR,MS,et al.RESULTS:Both of the two processe