贝诺酯的相转移催化合成

Synthesis of Benorylate by Phase-transfer Catalysis

摘要: 以聚乙二醇(PEG)为相转移催化剂,采用液一液相转移催化的方法,由乙酰水杨酰氯和对乙酰氨基苯酚制得高产率的贝诺酯,且反应时间短、操作简便。同时,考察了不同分于量的PEG对产率的影响。

Abstract: Benorylate was symthesized by phase-transfer catalysis from Scalicylic acid choorlde and acetaminophen with the yield of 97.0%.The synthesis was simple and rapid.Relationships between the yield and different moleCular weight PEC wer investigated.