不同厂家安定片的体外溶出度比较
Comparison of the Dissolution of Diazepam Tablets
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摘要: 采用转篮法研究了四个厂家6个批号安定片的体外溶出度,实验数据用威布尔分布模型拟合,求得Td、T50、m.结果表明:不同厂家生产的安定片溶出度差异显著(P<0.01),而同一厂家生产的不同批号的安定片溶出度无明显差异。Abstract: Dissolution of six batches of diazepam tablets from four pharmaceutical ftctorleswas studied by the rotating basket method. Td, T50 and M were calculated by Weibulldistribution. We did not find a significant difference of the dissolution rates between var