利福平对小鼠同种异体半心移植存活时间的影响

Rifampicin Prolongs Survival Time of Allogenic Heart Grafts in Mice

摘要: 利福平以500mg/kg 剂量连续灌胃两周,实验结果表明该药能明显地延长小鼠同种异体半心移植的存活时间,延缓移植排斥反应的发生,呈现明显的免疫抑制作用。

Abstract: The effects of Rifamplcin on transplantation immunity were investigated in mice.Afterp.o.administration of rifampicin 500 mg/kg per days for two weeks,it was found that,in compa-rism of rifampicin with the control group,the difference was very significant